Innovalve grew out of inventions and patents developed by Sheba Medical Center experts Prof. Ehud Raanani the director of Sheba’s Cardiovascular and Thoracic Center and Dr. Boris Orlev, head of the center’s Mitral Valve Surgery Unit. The company has developed an artificial mitral valve that can be replaced using a minimally-invasive catheter to help treat patients suffering from heart disease. The company achieved successful results in experiments on animals and is set to apply for FDA approval for human trials in the coming months. Among Innovalve’s investors is Edwards Lifesciences, a leader in cardiological valves.

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